LEISHMANICIDAL ACTIVITY OF FLAVONOIDS NATURAL AND SYNTHETIC: A MINIREVIEW

Autores

• Giani Maria CavalcanteITEP/PE
• Amanda Evanile da Silva CabralUNINASSAU/PE
• Camila Cássia SilvaUNINASSAU/PE

Resumo

Introduction: The Flavonoids are derivatives constituted of phenolic and are classified according to substitutions of pyran rings, are present in plants and your biological,pharmacological and medicinal properties were broadly registered. Objective: The aim of the study was realized a mini review about the leishmanicidal activity of flavonoidsisolated from vegetable and synthesized. Methods: the review was conducted used four databases which included SciFinder®, MEDLINE-PubMed, Web of Science andLILACS, used different combinations of the keywords. Results: A total of 1.366 abstracts were identified in databases, and according to the inclusion and exclusion criteria 24papers were selected to systematic review and your analysis showed that the leishmanicidal activity was performed with 41 isolated flavonoids of vegetal resource and 23synthesized flavonoids. Conclusion: was possible sees a promising future for the development of anti-parasitic drugs starting from flavonoids.

Palavras-chave

Leishmanicidal activity, Leishmania sp. Flavonoids.

Licença

Este capítulo está sob a Licença Creative Commons Atribuição-NãoComercial-SemDerivações 4.0 Internacional .

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