THERAPEUTIC APPLICATIONS OF GANODERMA LUCIDUM: PROGRESS AND LIMITATIONS

Ganoderma lucidum presents different nomenclatures that change according to the countries where it is used. This mushroom has been used for more than 4 thousand years to treat different pathologies. It is used in different presentations and the dosage varies according to the pathology treated. There are many compounds that form its chemical constitution. In vitro assays emphasize its antitumor, immunomodulatory and antioxidant properties. In vivo studies highlight its properties of hepatoprotection and antiglycemic are also described. Although its therapeutic use is variable, its toxicity and safety in pregnancy, childhood and in the elderly is still unknown. Thus, many studies are necessary to determine their safe and rational use in therapeutic.